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Nucleofill Eyes – Tear Trough Rejuvenation – 2ml


With the lowest molecular weight in its class, Nucleofill Eyes (formerly Soft Plus) is an advanced polynucleotide-based gel primarily intended for rejuvenation of the tear trough. Its bioregenerative effects work on multiple levels – stimulating fibroblast production, lessening wrinkles, reducing hyperpigmentation (dark circles), and restoring youthful epidermal density.

This product comes in the form of a pre-filled 2ml syringe. Needles not included. Select your preferred quantity below.

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SKU GUS-2410-SKI Categories , , , , All prices are as displayed.


About the Nucleofill range

The Nucleofill range of Eyes (formerly Soft Plus), 20 (formerly Medium), Medium Plus and Strong Plus products by Promoitalia represents a regenerative approach to treatments with a single key active ingredient. Each product in the Nucleofill range is intended for its own facial or scalp application, and each contains its own specific concentration of polymerised polynucleotides. These are powerful free radical fighters that help stimulate fibroblast growth in the epidermis and dermis, as well as hair density in the scalp region. Polynucleotides also possesses strong hydrophilic properties that act as magnets for water molecules, encouraging them to bind to and hydrate the skin. In all, the Nucleofill range can help restore some of the key characteristics of a youthful appearance that are otherwise lost with age.

Nucleofill Eyes highlights:

  • Premium quality, regenerative product ideal for application in the tear trough region
  • A first-line treatment choice for dark circles, periocular wrinkles and crepey undereye skin
  • Sterile, pyrogen-free formula with 7.5mg per 1 millilitre of polymerised polynucleotides (15mg per 2ml)
  • Restores youthful soft tissue turgor, density and volume – working at both deep and superficial tissue levels
  • Presents an an alternative to dermal fillers for tear trough rejuvenation, without risk of lumping or discolouration
  • An alternative to skin boosters: can be used across other delicate facial regions
  • Convenient pre-filled product: 2ml covers 1-2 separate treatments
  • Notes:


    1. Option 1: Superficial mesotherapy micro-applications into the lower eyelid, 0.5cm apart, 0.05ml per point, evenly distributed;
    2. Option 2: Cannula (linear retrograde) into the hypodermis. 0.2ml per pass, 0.7cm apart, for deeper tissue rejuvenation when required
    3. Frequency: 2 sessions, two weeks apart. For more significant undereye issues, complete another two sessions spaced 21 days apart thereafter;
    4. Maintenance: 1 session every 3-6 months.

    One sterile 2ml Nucleofill Eyes product can cover up to two individual applications.

    Results: after the initial treatment and within 3-5 days of application, the undereye region will look rejuvenated. Thereafter, it takes a few weeks for the full effects of the biostimulation process to be realised. This continues after the treatment and can ultimately help to regenerate hyperpigmented and wrinkled undereye skin with long-lasting improvements in thickness, firmness and elasticity.

    Product disclaimer: For information on risks and side effects, read the box’s leaflet insert and ask your doctor or pharmacist. Any advice given acts as a guide only; individual suitability and treatment frequency must be pre-assessed. As body chemistry varies, effectiveness and reactions may also differ. Intended for use by professionals. Do not use on broken skin or in areas of infection. Do not use if hypersensitive to polynucleotides. Do not use in cases of hypertrophy of the adipose panniculus (fat pouches) in the lower eyelid or edematous (liquid) eye bags. Consult a qualified practitioner before use in pregnant or breastfeeding women. Store at room temperature. If seal is broken, do not use.

    Additional information

    Weight0.044 kg
    Dimensions18.7 × 7 × 3.3 cm



    7.5mg/1ml Polynucleotides


    Enclosed in box

    Shelf Life

    2 years from date of manufacture


    1 box (2ml syringe)

    We neither offer nor purport to offer any medical advice on this website, our official social media channels, via our customer service personnel nor via any approved affiliates. We will therefore not assume liability for any third parties (either customers or order recipients) involved either directly or indirectly in the procurement and/or usage of products ordered from this website.

    For any injectable, microneedling and/or topical product: we advise that you conduct a patch test and wait in accordance with manufacturer advice (as per the product's packaging and/or enclosed literature) before proceeding to use it. You must agree not to use any products purchased on this website without taking appropriate measures and precautions against any potential harm that may arise. We assume no liability for the negative consequences of self-use.

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